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| Development of on Chip Devices for Life Science Applications
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Full
text: |
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Source |
International Journal of Engineering (IJE) |
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Table of Contents |
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Download
Complete Issue PDF(2.9MB) |
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Volume: 3 Issue: 2 |
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Pages: 85-219 |
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Publication
Date: April 2009 |
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ISSN
(Online): 1985-2312 |
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Pages |
148 - 158 |
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Author(s) |
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Published
Date |
18-05-2009 |
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Publisher |
CSC
Journals, Kuala Lumpur,
Malaysia |
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ADDITIONAL
INFORMATION |
| Keywords Abstract References Cited by Related Articles Collaborative
Colleague |
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KEYWORDS: Microfluidics, Biosensors, Bioreactors, micropumps |
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| This work reports on diverse technologies implemented for fabricating microfluidic devices such as biomedical micro sensors, micro pumps, bioreactors and micro separators. UV depth lithography and soft lithography were applied in the fabrication processes using different materials, for example SU-8, polydimethylsiloxane (PDMS), silicon, glass and ceramics. Descriptions of the fabrication process of completed devices and their performance are provided. Experimental tests and results are presented where available.
This work highlights the importance of down scaling in producing efficient devices suitable for life science applications using diverse materials that are compatible with chemical and biomedical applications.
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| 1 |
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F. Laermer, A. Urban. “Challenges, developments and applications of silicon deep reactive ion etching”. Microelectron. Eng. 67-68, 349-355, 2003
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H. Khoo, K. Liu, F. Tseng. “Mechanical strength and interfacial failure analysis of cantilevered SU-8 microposts”, J. Micromech. Microeng. 13:82-831, 2003.
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4. B. Hoxhold, M. Kirchhoff, S. Bütefisch, S. Büttgenbach. “SMA Driven Micro Grippers Combining Piezo-Resistive Gripping Force Sensors with Epon SU-8 Mechanics”. XX Eurosensors 2006, Göteborg, 2006.
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5. H. Sato, H. Matsumura, S. Keino, S. Shoji. “An all SU-8 microfluidic chip with built-in 3D fine microstructures”. J. Micromech. Microeng. 16:2318-2322, 2006.
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6. J. Ribeiro, G. Minas, P. Turmezei, R. Wolffenbuttel, J. Correia. “A SU-8 fluidic microsystem for biological fluids analysis”. Sensors and Actuators A, 123-124:77-81, 2005
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7. A. Al-Halhouli, I. Kampen, T. Krah, S. Büttgenbach. “Nanoindentation testing of SU-8 photoresist mechanical properties”. Microelectronic Engineering, 85:942-944, 2008.
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8. M. Feldmann, A. Waldschik, S. Büttgenbach. “A novel fabrication process for 3D-multilayer micro mixers”. Proc. 8th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences. Malmö, 2004.
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9. S. Charati, S. Stern. “Diffusion of gases in silicone polymers: molecular dynamics simulations”. Macromolecules, 31:5529-5535, 1998.
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10. W-J. Chang, D. Akin, M. Sedlak, M. R. Ladisch, R. Bashir. “Poly(dimethylsiloxane) (PDMS) and silicon hybrid biochip for bacterial culture”. Biomedical Microdevices, 5:281-290, 2003.
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11. S. H. de Kock, J. C. du Preez, S. G. Kilian. “Anomalies in the growth kinetics of Saccharomyces cerevisiae strains in aerobic chemostat cultures”. Journal of Industrial Microbiology and Biotechnology, 24:231-236, 2000.
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12. M. Feldmann, S. Demming, C. Lesche, S. Büttgenbach. “Novel Electromagnetic micropump”. Proceedings of SPIE, 2007.
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13. R. Wilke, S. Büttgenbach. “A micromachined capillary electrophoresis chip with fully integrated electrodes for separation and electrochemical detection”. Biosensors and Bioelectronics, 19:149-153, 2003.
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14. S. Demming, A. Jansen, E. Franco-Lara, R. Krull, S. Büttgenbach. “Mikroreaktorsystem als Screening-instrument für biologische Prozesse“. Proceedings of MicroSystemTechnology Congress, Dresden, 2007.
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15. A. Edlich, S. Demming, M. Vogl, S. Büttgenbach, E. Franco-Lara, R. Krull. “Microfluidic Screening Reactor for Estimation of Biological Reaction Kinetics”. Proceedings of 1st European Congress on Microfluidics, Bologna, 2008.
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16. J. M. Gancedo. “Control of pseudohyphae formation in Saccharomyces cerevisiae”. FEMS Microbiology Reviews, 25:107-123, 2001.
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17. M. Michalzik, A. Balck, S. Büttgenbach, L. Al-Halabi, M. Hust, S: Dübel. “Microsensor System for Biochemical and Medical Analysis”, Proc. XX Eurosensors, Göteborg, 2006.
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18. G. Sauerbrey. “Verwendung von Schwingquarzen zur Wägung dünner Schichten und zur Mikrowägung“. Zeitschrift für Physik A, 155:1546-1551, 1959.
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19. C. K. O'Sullivan, G. Guilbault. “Commercial quartz crystal microbalances - theory and applications”. Biosensors and Bioelectronics, 14:663-670, 1999.
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20. A. Balck, M. Michalzik, M. Wolff, U. Reichl, S. Büttgenbach. “Influenza virus detection in vaccine production with a quartz crystal microbalance”. Proceedings of Biosensors 2008, Shanghai, 2008.
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21. M. Michalzik, L. Al-Halabi, A. Balck, M. Hust, S: Dübel, S. Büttgenbach. “A mass sensitivemicrofluidic immunosensor for CRP-detection using functional monolayers”. Proceedings of Biosensors 2008, Shanghai, 2008a.
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22. M. Michalzik, A. Balck, L. Al-Halabi, M. Hust, S: Dübel, S. Büttgenbach. “Massensensitives Sensor-Fließsystem zur CRP-Diagnostik”. Proceedings of. Mikrosystemtechnikkongress, Dresden, 2007.
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23. J. Rabe, S. Büttgenbach, B. Zimmermann, P. Hauptmann. Proceedings of IEEE/EIA International Frequency Control Symposium 2000.
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24. A. Balck, A. T. Al-Halhouli, S. Büttgenbach. “Separation of blood cells in Y- microchannels”. ICTEA09, Abu Dhabi, 2009.
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25. A. Majid. “Electrostatic and Electromagnetic fields actuators for MEMS AD/DA converters” International Journal of Engineering, 2(1):35-41, 2007.
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26. M. Michalzik, A. Balck, C. Ayala, N. Lucas, S. Demming, A. Phataralaoha, S. Büttgenbach. “A Hydrogel-Actuated Microvalve for Medical and Biochemical Sensing”. Actuator 08, Bremen, 2008b.
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27. V. C. Ayala, M. Michalzik, S. Harling, H. Menzel, F. A. Guarnieri, S. Büttgenbach. “Design, Construction and Testing of a Monolithic pH-Sensitive Hydrogel-Valve for Biochemical and Medical Application”. Journal of Physics, Conference Series 90, 2007.
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| 28 |
M. Al-Shurman, S-M. Yoo, and S. Park, “Black Hole Attack in Mobile Ad Hoc Networks,” ACM Southeast Regional Conf. 2004.
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| 1 |
A. T. Al-Halhouli, A. Waldschik, M. I. Kilani, S. Büttgenbach: “Gentle Micropump Based on Microelectromagnetic Actuator” NSTI Nanotech, 2(2010), pp. 340-343, June 2010.
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A.B. Mattos, T.A. Freitas, V.L. Silva, R.F. Dutra, “A Dual Quartz Crystal Microbalance For Human Cardiac Troponin T In Real Time Detection”, Sensors and Actuators B: Chemical, 161(1), pp. 439–446, January 2012.
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Institut für Mikrotechnik, TU Braunschweig
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doc88.com
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The Collaborative Research Center SFB 578
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DOC-TXT
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yasni
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| Stephanus Büttgenbach : Colleagues
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| Anne Balck : Colleagues
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| Stefanie Demming : Colleagues
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| Claudia Lesche : Colleagues
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| Monika Michalzik : Colleagues
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| Alaaldeen : Colleagues
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